What are the symptoms of ectodermal dysplasia?

What are the symptoms of ectodermal dysplasia?


  • Abnormal nails.
  • Abnormal or missing teeth, or fewer than normal number of teeth.
  • Cleft lip.
  • Decreased skin color (pigment)
  • Large forehead.
  • Low nasal bridge.
  • Thin, sparse hair.
  • Learning disabilities.

Is ectodermal dysplasia serious?

This depends on the specific type of ectodermal dysplasia a person has. Even within each type, people can be affected differently depending on the combination of symptoms they have. Any one of the abnormalities may be mild or severe.

How long do people with ectodermal dysplasia live?

Does ectodermal dysplasia affect lifespan? Lifespan is normal in nearly all types of ectodermal dysplasia.

Can ectodermal dysplasia be cured?

The condition is present from birth but may not be detected until later in childhood. ED is caused by altered genes. It can be inherited within families who have the genetic defect, or it can occur in families without a history of the condition. ED cannot be cured, but the symptoms can be treated or managed.

Is ectodermal dysplasia rare?

All of the 180+ different types of ectodermal dysplasias are considered “rare” because they affect less than 200,000 people in the United States.

What is the survival rate of ectodermal dysplasia?

Survival rates ranged from 88.5% to 97.6% in patients with ectodermal dysplasia (n=71 patients, three studies) and from 90% to 100% in patients with tooth agenesis (n=178 patients, five studies).

How does ectodermal dysplasia affect hair?

Hair growth in some types of ectodermal dysplasia can be slow, meaning haircuts might not be needed as often as in unaffected family members. After puberty, hair symptoms improve for some individuals. They may see some increase in hair density and thickness, as well as darkening of the hair.

Is ectodermal dysplasia an autoimmune disease?

Thus ectodermal dysplasia may be an autoimmune disease affecting structures developed from embryonic ectodermal cells.

Does ectodermal dysplasia affect females?

Hypohidrotic ectodermal dysplasia (HED) is usually transmitted as an X-linked recessive trait in which the gene is carried by the female and manifested in male.

Is ectodermal dysplasia hereditary?

Ectodermal dysplasia is a rare hereditary disorder with a characteristic physiognomy. It is a genetic disorder affecting the development or function of the teeth, hair, nails and sweat glands.