What is Z0011?

The American College of Surgeons Oncology Group Z0011 (ACOSOG Z0011) randomized clinical trial was designed to determine whether SLND alone yielded survival outcomes that were noninferior to that obtained with ALND in women with a limited number of sentinel node metastases undergoing breast-conserving surgery and …

What did the Acosog Z0011 study conclude?

Background: The early results of ACOSOG Z0011 showed that selected sentinel node (SN)-positive patients (pts) treated with sentinel node biopsy (SNB), whole breast irradiation, and adjuvant systemic therapy experienced overall survival (OS) and disease-free survival (DFS) not inferior to those treated with axillary …

What was the Z11 trial for breast cancer?

The Z11 trial demonstrated a subgroup of patients with low axillary burden who do not benefit from axillary lymph node dissection (ALND) at short-term follow-up when treated with adjuvant whole-breast radiotherapy and systemic therapy.

Is axillary node dissection needed after mastectomy with positive sentinel nodes?

Background: A positive sentinel lymph node has traditionally required subsequent axillary dissection.

What is axillary web syndrome?

Axillary Web Syndrome (AWS) is also called cording, tethering, or banding. It is a condition that may happen in the arm, armpit, trunk, or breast, after surgery and treatment for breast cancer. • You may see thick or thin bands, or cords, in the armpit, which may run down the arm.

What is a full axillary lymph node dissection?

An axillary lymph node dissection (ALND) is surgery to remove lymph nodes from the armpit (underarm or axilla). The lymph nodes in the armpit are called axillary lymph nodes. An ALND is also called axillary dissection, axillary node dissection or axillary lymphadenectomy.

What are the axillary lymph nodes?

Lymphatic system and axillary nodes Lymph nodes are small clumps of immune cells that act as filters for the lymphatic system. They also store white blood cells that help fight illness. The lymph nodes in the underarm are called axillary lymph nodes. If breast cancer spreads, this is the first place it’s likely to go.

What are clear margins for DCIS?

A new guideline put out by three national cancer organizations says that 2-millimeter (about one-eighth of an inch) clean margins should be the standard for women diagnosed with ductal carcinoma in situ (DCIS) treated with lumpectomy and whole-breast radiation.

How do I get rid of underarm cording?

How to treat cording

1. Gentle stretching: It’s very important to stretch your arm every day to decrease pain and increase your arm’s mobility.
2. Massage therapy: Massaging the area may help reduce pain and tightness.
3. Physical therapy: Physical therapy is highly effective at treating cording.

How common is re excision after lumpectomy?

Results: For 6,725 patients undergoing initial lumpectomy for cancer, 328 surgeons reported 1,451 (21.6 %) patients had one or more re-excisions. The most common reasons for re-excision were ink positive margins in 783 (49.7 %), margin <1 mm (34.3 %), and margin 1-2 mm (7.2 %).