Is transcutol soluble in water?

The highest mole fraction solubility (1.61 × 10−1) of trans-resveratrol was observed in pure Transcutol HP at 313.15 K, whereas the lowest value (1.29 × 10−6) was found in pure water at 288.15 K.

What is transcutol P?

Transcutol® P is a high purity grade of diethylene glycol monoethyl ether (DEGEE) (Figure 1) manufactured by the condensation of ethylene oxide and ethanol, followed by distillation. The presence of an ether and an alcohol function explains the exceptional solubilizing capacity of this solvent.

What is transcutol CG?

Transcutol CG is a superior solubilizer and efficacy booster for cosmetic formulations. It enhaces penetration of cosmetic actives, helps repair split ends, improves color fixation of self-tanning products with DHA, and many additional uses.

What is diethylene glycol monoethyl ether used for?

Background: The solvent diethylene glycol monoethyl ether (DEGEE) is currently used in over 500 cosmetic products and has enabled the formulation of a topical 5% dapsone gel for the treatment of acne.

What is carbitol used for?

Solvent used to facilitate penetration into fibers and to promote the production of intense, bright shades; it features a high boiling point and low vapor pressure. Also an important solvent in nongrain-raising wood stains and serves as a component of industrial cleaners.

How is Ethoxydiglycol made?

Ethoxydiglycol, also known as diethylene glycol monoethyl ether or DEGEE, is produced by the ethoxylation of ethanol. Ethoxylation is a chemical reaction in which ethylene oxide is added to a substrate. In this case, the substrate is ethanol, a type of alcohol.

What is transcutol HP?

Highest-purity solvent and solubilizer for solubility and bioavailability enhancement for oral and alternative routes.

What is labrafil?

A nonionic water-dispersible surfactant for lipid-based formulations to solubilize and increase oral bioavailability of poorly water-soluble APIs.

What is Ethoxydiglycol reagent?

Ethoxydiglycol also known as diethylene glycol monethyl ether, is a cosmetic grade solvent that conforms to the current USP/NF monographs. Ethoxydiglycol is particularly appropriate for skin care preparations where it acts as an excellent solvent and carrier.

Is diethylene glycol monoethyl ether toxic?

Diethylene glycol mono- ethyl ether is of low acute toxicity (oral LD50 > 3000 mg/kg body weight). Systemic toxicity was observed after rats and mice were given oral doses of diethylene glycol monoethyl ether above 2000 mg/kg body weight.

Is diethylene glycol flammable?

Diethylene Glycol Dinitrate is FLAMMABLE and REACTIVE and a DANGEROUS FIRE and EXPLOSION HAZARD.

Why is there a shortage of Ethoxydiglycol?

Experts say a key ingredient, called ethoxydiglycol, has been facing supply problems in recent weeks. The ingredient is imported from abroad and used extensively in many high-end skincare products including fake tan and skin creams.

Is Ethoxydiglycol water soluble?

Ethoxydiglycol, also known as diethylene glycol monethyl ether, is a cosmetic grade solvent. It is soluble in water and oil. Ethoxydiglycol is primarily used to dissolve ingredients to decrease viscosity. This solvent is widely used for skin care product preparations where it acts as an excellent solvent and carrier.

Is diethylene glycol a glycol ether?

Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol, a hydroxypolyether and a glycol ether.

What is Ethoxydiglycol made from?

Is diethylene glycol monoethyl ether flammable?

Water soluble. DIETHYLENE GLYCOL MONOMETHYL ETHER is a ether-alcohol derivative. The ether being relatively unreactive. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents.

What is the density of diethylene glycol?

1.12 g/cm³Diethylene glycol / Density

Is glycol a fire hazard?

FIRE FIGHTING INFORMATION:

Ethylene glycol is combustible. Extinguish fires using an agent suitable for the type of surrounding fire. Use “alcohol” foam, dry chemical, or carbon dioxide. Keep run-off water out of sewers and water sources.

Why is there a fake tan shortage?

Lack of availability and skyrocketing prices have led to some manufacturers being unable to get their hands on the key ingredient, causing major disruption and a predicted fake tan shortage.

Why is there a tan shortage?

It’s been really difficult to manage the supply chain. “One of the reasons for the shortage is because tan has become really popular in China and that’s where our raw ingredients come from. As their market grows so does the demand for the ingredients.”

What is the difference between MEG and DEG?

The MEG manufactured is of minimum 99.5 per cent purity and meets the required UV transmittance values specified by polyester manufacturers. DEG is a stable, high-boiling, odourless and hygroscopic liquid, which is completely miscible in water.

Is diethylene glycol in cigarettes?

Diethylene Glycol (DEG) Humectants, or moisturizing agents, are used in cigarette tobacco blends to assist with aerosol formation and thus make cigarette smoke “milder.” The more that nicotine can be dissolved in the tar droplets, the less irritating the smoke is to the consumer’s throat and the easier it is to inhale.

What is the difference between ethylene glycol and diethylene glycol?

The key difference between ethylene glycol and diethylene glycol is that an ethylene glycol molecule is an individual molecule whereas diethylene glycol molecule is formed by the combination of two ethylene glycol molecules via an ether bond.

Is dried antifreeze toxic?

Ethylene glycol breaks down into toxic compounds in the body. Ethylene glycol and its toxic byproducts first affect the central nervous system (CNS), then the heart, and finally the kidneys. Ingesting enough can cause death. Ethylene glycol is odorless.

Can propylene glycol explode?

* Propylene Glycol Dinitrate is EXPLOSIVE under fire conditions. * Use dry chemical, CO2, water spray, or a foaming agent. * POISONOUS GASES ARE PRODUCED IN FIRE, including Nitrogen Oxides. * CONTAINERS MAY EXPLODE IN FIRE.